Age- and sex-dependent alterations of jejunal microbiota in Fischer 344 rats fed with a high-fructose, high-fat diet: depletion of Lactobacillus intestinalis in small bowel contents
Collectively, HFHFD induces age- and sex-dependent dysbiosis in the jejunum, and <i>L. intestinalis</i> may serve as a potential probiotic for metabolic dysfunction-associated steatotic liver disease.
Authors
- Nayoung Kim (ORCID: https://orcid.org/0000-0002-7170-3307)
- Sungchan Ha
- Chin-Hee Song
Institutions
- Seoul National University (KR)
- New Generation University College (ET)
- Seoul National University Bundang Hospital (KR)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2026-03-02
- DOI
- https://doi.org/10.3389/fmicb.2026.1779112
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Seoul National University Bundang Hospital
- Seoul National University
- Ministry of Trade, Industry and Energy
- National Institutes of Health