Clinical effectiveness of esophageal stricture dilation using an improved endoscopic attachment cap in adults with eosinophilic esophagitis

The improved endoscopic attachment cap has the following new features: 1) more rounded tip; 2) stepwise dilation in two 1-mm increments; 3) softer plastic, ensuring better contact with the endoscope tip; and 4) improved adhesive tape. We evaluated the feasibility and effectiveness of one-time esophageal stricture dilation using the new device in adults with eosinophilic esophagitis (EoE).Patients prospectively included in the Swiss EoE cohort with esophageal strictures (diameter ≤16 mm) and stricture-related symptoms underwent dilation with the new device. Symptoms were assessed using the Eosinophilic Esophagitis Activity Index patient-reported outcomes instrument before and 2 weeks after a single dilation.60 patients (median age 42 years; 75% male) were evaluated. Bougienage was successful in all patients. Median esophageal diameter increased from 12 mm (interquartile range [IQR] 11-14) to 16 mm (IQR 14-16; P < 0.001). Median symptom severity dropped from 36 points (IQR 22-62) to 0 (IQR 0-12; P < 0.001). No device became detached and no severe adverse events were reported. Post-dilation pain was recorded in 31.7% (19/60).Esophageal stricture dilation in adults with EoE using the improved endoscopic attachment cap was feasible, clinically effective, and environmentally friendly.

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Publication Details

Journal
Universität Zürich, ZORA
Published
2025-10-01
DOI
https://doi.org/10.5167/uzh-292692
Primary Topic
Esophageal and GI Pathology
Type
article
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article

Clinical effectiveness of esophageal stricture dilation using an improved endoscopic attachment cap in adults with eosinophilic esophagitis

Catherine Saner, Thomas Greuter, Ekaterina Safroneeva, Alex Straumann et al.
Universität Zürich, ZORA
Esophageal and GI Pathology
article

Clinical effectiveness of esophageal stricture dilation using an improved endoscopic attachment cap in adults with eosinophilic esophagitis

Catherine Saner, Thomas Greuter, Ekaterina Safroneeva, Alex Straumann, Philipp Schreiner, Andrea Kreienbuehl, Alain M Schoepfer, Luc Biedermann, Jeanine Wakim El-Khoury
article en

Abstract

The improved endoscopic attachment cap has the following new features: 1) more rounded tip; 2) stepwise dilation in two 1-mm increments; 3) softer plastic, ensuring better contact with the endoscope tip; and 4) improved adhesive tape. We evaluated the feasibility and effectiveness of one-time esophageal stricture dilation using the new device in adults with eosinophilic esophagitis (EoE).Patients prospectively included in the Swiss EoE cohort with esophageal strictures (diameter ≤16 mm) and stricture-related symptoms underwent dilation with the new device. Symptoms were assessed using the Eosinophilic Esophagitis Activity Index patient-reported outcomes instrument before and 2 weeks after a single dilation.60 patients (median age 42 years; 75% male) were evaluated. Bougienage was successful in all patients. Median esophageal diameter increased from 12 mm (interquartile range [IQR] 11-14) to 16 mm (IQR 14-16; P < 0.001). Median symptom severity dropped from 36 points (IQR 22-62) to 0 (IQR 0-12; P < 0.001). No device became detached and no severe adverse events were reported. Post-dilation pain was recorded in 31.7% (19/60).Esophageal stricture dilation in adults with EoE using the improved endoscopic attachment cap was feasible, clinically effective, and environmentally friendly.

Universität Zürich, ZORA
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Esophageal and GI Pathology
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Clinical effectiveness of esophageal stricture dilation using an improved endoscopic attachment cap in adults with eosinophilic esophagitis — Catherine Saner, Thomas Greuter, et al. · Universität Zürich, ZORA (2025) | TGRS Research Map | TGRS