Validation and Extension of a Risk Calculator to Predict Mood Recurrence in Young People with Bipolar Disorder

The mood recurrence RC demonstrated good discrimination for both threshold and subthreshold mood recurrences in an independent young adult cohort, consistent with prior youth and adult validations. Validation now spans across developmental stages and different degrees of severity of mood symptoms opening the opportunity for clinical implementation to provide personalized monitoring and early intervention for people with BD.

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Publication Details

Journal
medRxiv
Published
2026-03-02
DOI
https://doi.org/10.64898/2026.02.20.26346717
Primary Topic
Bipolar Disorder and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Validation and Extension of a Risk Calculator to Predict Mood Recurrence in Young People with Bipolar Disorder

Jessica C. Levenson, Ava Avolio, John Merranko, Tina R Goldstein et al.
medRxiv
Bipolar Disorder and Treatment
article

Validation and Extension of a Risk Calculator to Predict Mood Recurrence in Young People with Bipolar Disorder

Jessica C. Levenson, Ava Avolio, John Merranko, Tina R Goldstein, Danella Hafeman, Mary Kay Gill, Boris Birmaher
article en

Abstract

The mood recurrence RC demonstrated good discrimination for both threshold and subthreshold mood recurrences in an independent young adult cohort, consistent with prior youth and adult validations. Validation now spans across developmental stages and different degrees of severity of mood symptoms opening the opportunity for clinical implementation to provide personalized monitoring and early intervention for people with BD.

medRxiv
University of Pittsburgh (US)
National Institute of Mental Health
Reduced inequalities, Peace, Justice and strong institutions
Openalex Percentile: Top 44%
Bipolar Disorder and Treatment
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