Preoperative decision tree model for predicting pulmonary valve-sparing repair in humanitarian pediatric tetralogy of fallot patients

Pulmonary valve-sparing repair in Tetralogy of Fallot is associated with better long-term outcomes, but its feasibility remains uncertain in pediatric humanitarian patients, who often present late, with complex anatomy and comorbidities. To develop a simple and interpretable decision tree model to predict the likelihood of pulmonary valve-sparing repair based on preoperative data in a humanitarian pediatric cohort. A post-hoc classification and regression tree analysis was conducted on 115 pediatric humanitarian patients with Tetralogy of Fallot who underwent surgical correction at our center, between 2019 and 2023. Predictor variables included demographic, anthropometric, and anatomical parameters. The model achieved an overall accuracy of 80.0%, with a sensitivity of 88.2% and specificity of 56.7%. The pulmonary valve annulus diameter (> 0.855 cm) was the primary discriminator for pulmonary valve-sparing repair. A simple decision tree model using preoperative anatomical variables may support surgical planning in humanitarian contexts. Its interpretability and high sensitivity suggest potential value as a preoperative triage and planning aid.

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Publication Details

Journal
Journal of Cardiothoracic Surgery
Published
2026-03-02
DOI
https://doi.org/10.1186/s13019-026-03882-8
Primary Topic
Congenital Heart Disease Studies
Type
article
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article

Preoperative decision tree model for predicting pulmonary valve-sparing repair in humanitarian pediatric tetralogy of fallot patients

Jalal Jolou, Ana Abecasis, Abdelkhalek Mouloudi, Tomasz Nalecz et al.
Journal of Cardiothoracic Surgery
Congenital Heart Disease Studies
article

Preoperative decision tree model for predicting pulmonary valve-sparing repair in humanitarian pediatric tetralogy of fallot patients

Jalal Jolou, Ana Abecasis, Abdelkhalek Mouloudi, Tomasz Nalecz, Telmo Pereira, Tornike Sologashvili, Vitor Mendes
article en

Abstract

Pulmonary valve-sparing repair in Tetralogy of Fallot is associated with better long-term outcomes, but its feasibility remains uncertain in pediatric humanitarian patients, who often present late, with complex anatomy and comorbidities. To develop a simple and interpretable decision tree model to predict the likelihood of pulmonary valve-sparing repair based on preoperative data in a humanitarian pediatric cohort. A post-hoc classification and regression tree analysis was conducted on 115 pediatric humanitarian patients with Tetralogy of Fallot who underwent surgical correction at our center, between 2019 and 2023. Predictor variables included demographic, anthropometric, and anatomical parameters. The model achieved an overall accuracy of 80.0%, with a sensitivity of 88.2% and specificity of 56.7%. The pulmonary valve annulus diameter (> 0.855 cm) was the primary discriminator for pulmonary valve-sparing repair. A simple decision tree model using preoperative anatomical variables may support surgical planning in humanitarian contexts. Its interpretability and high sensitivity suggest potential value as a preoperative triage and planning aid.

Journal of Cardiothoracic Surgery
University of Geneva (CH), Polytechnic Institute of Coimbra (PT), University Hospital of Geneva (CH), Instituto de Investigação Científica Tropical (PT), Geneva College (US), University of Coimbra (PT), Universidade Nova de Lisboa (PT)
Openalex Percentile: Top 38%
Congenital Heart Disease Studies
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Preoperative decision tree model for predicting pulmonary valve-sparing repair in humanitarian pediatric tetralogy of fallot patients — Jalal Jolou, Ana Abecasis, et al. · Journal of Cardiothoracic Surgery (2026) | TGRS Research Map | TGRS