Safety and Efficacy of Direct Oral Anticoagulants Versus Warfarin in Adults With Durable Left Ventricular Assist Devices: A Multicenter Retrospective Cohort Study

In this multicenter cohort, DOACs were associated with improved long-term survival and comparable safety outcomes relative to warfarin in LVAD patients. These findings suggest DOACs may be a viable alternative, but larger prospective studies are warranted.

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Publication Details

Journal
American Journal of Therapeutics
Published
2026-03-02
DOI
https://doi.org/10.1097/mjt.0000000000002033
Primary Topic
Mechanical Circulatory Support Devices
Type
article
Field-Weighted Citation Impact
0.00
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article

Safety and Efficacy of Direct Oral Anticoagulants Versus Warfarin in Adults With Durable Left Ventricular Assist Devices: A Multicenter Retrospective Cohort Study

Mahmoud Barbarawi, Shareef Mansour, Mubariz Ahmed Hassan, Ahmad Al‐Abdouh et al.
American Journal of Therapeutics
Mechanical Circulatory Support Devices
article

Safety and Efficacy of Direct Oral Anticoagulants Versus Warfarin in Adults With Durable Left Ventricular Assist Devices: A Multicenter Retrospective Cohort Study

Mahmoud Barbarawi, Shareef Mansour, Mubariz Ahmed Hassan, Ahmad Al‐Abdouh, Krishna Sagar Gajula, Ahmad Jabri, Mohammed Mhanna, Omar Mousa, Ernesto Ruiz Duque
article en

Abstract

In this multicenter cohort, DOACs were associated with improved long-term survival and comparable safety outcomes relative to warfarin in LVAD patients. These findings suggest DOACs may be a viable alternative, but larger prospective studies are warranted.

American Journal of Therapeutics
University of Iowa (US), University of Connecticut (US), University of Kentucky (US), Ollscoil na Gaillimhe – University of Galway (IE), Dar Al-Shifa Hospital (PS), University Hospital Galway (IE), Beaumont Hospital, Royal Oak (US), The University of Texas Medical Branch at Galveston (US), UConn Health (US)
Openalex Percentile: Top 40%
Mechanical Circulatory Support Devices
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