Role of Dual-Phase 18F FP-CIT PET for Subtyping of Multiple System Atrophy

Dual-phase 18F FP-CIT PET provides a single-session approach for capturing both perfusion and DAT status, enabling subtype classification and disease severity assessment in early MSA. Putaminal abnormality on early FP-CIT PET might be less sensitive than MRI, and asymmetric cerebellar perfusion could be a useful marker for differential diagnosis of ataxia.