Prevalence of actionable pharmacogenomic variants in Brazilian patients with cancer

Nearly all Brazilian patients with cancer carried at least one actionable PGx variant, highlighting the potential impact of PGx-guided therapy in oncology. These results underscore the value of integrating pharmacogenomic strategies into clinical practice in Brazil.

Authors

Institutions

Publication Details

Journal
Frontiers in Pharmacology
Published
2026-03-02
DOI
https://doi.org/10.3389/fphar.2026.1736887
Primary Topic
Pharmacogenetics and Drug Metabolism
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Prevalence of actionable pharmacogenomic variants in Brazilian patients with cancer

Mariana Rodrigues Botton, Nathan Araujo Cadore, Marina Bessel, Jaqueline Bohrer Schuch et al.
Frontiers in Pharmacology
Pharmacogenetics and Drug Metabolism
article

Prevalence of actionable pharmacogenomic variants in Brazilian patients with cancer

Mariana Rodrigues Botton, Nathan Araujo Cadore, Marina Bessel, Jaqueline Bohrer Schuch, Glaucio Bertollo, Flávio Silva Brandão, A. Nogueira-Rodrigues, Gustavo Werutsky, Cláudia Bordignon, Gabriel S. Macedo, Eduardo Kowalski-Neto, Giovana Dallaio Curzel, Cristiano Pádua Souza, Alessandra Notari, E. Reche Santos, Christina Oppermann, Juliana De Menezes, Ruffo Freitas-Junior, Williams Fernandes Barra, Pedro E. R. Liedke, Vitor F. Vasconcellos, Lilian A. R. Barros, Mahira L. Rosa, Daniela L. C. Louzeiro, Daniela D. Rosa, Angélica C. De Baumont, André L. C. Mancini, Henrique G. Ascenco, Aline B. L. Gongora
article en

Abstract

Nearly all Brazilian patients with cancer carried at least one actionable PGx variant, highlighting the potential impact of PGx-guided therapy in oncology. These results underscore the value of integrating pharmacogenomic strategies into clinical practice in Brazil.

Frontiers in PharmacologyVol. 17
Universidade Federal de Minas Gerais (BR), Ministry of Education (BR), Universidade Federal do Rio Grande do Sul (BR), Universidade Federal de Pelotas (BR), Universidade Estadual de Santa Cruz (BR), Hospital Moinhos de Vento (BR), Hospital Universitário de Santa Maria (BR), Hospital de Câncer de Barretos (BR), Liga Contra el Cancer (PE), University Gama Filho (BR), Hospital de Clínicas de Porto Alegre (BR), D’Or Institute for Research and Education (BR), Hospital Araújo Jorge (BR), Hospital Nossa Senhora da Conceição (BR), Grupo Santa Casa de Belo Horizonte (BR), Santa Casa de Misericórdia de Marília (BR), Hospital São Lucas da PUCRS (BR), Instituto Brasileiro de Controle do Câncer (BR), Fundação Getulio Vargas (BR), Universidade Federal do Pará (BR)
Good health and well-being
Openalex Percentile: Top 35%
Pharmacogenetics and Drug Metabolism
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.