Scedosporium apiospermum endocarditis in an immunocompetent patient: a case report and literature review

S. apiospermum endocarditis carries a grave prognosis. Among 18 reviewed articals, 19 patients succumbed to the infection, 7 of whom were diagnosed postmortem, precluding therapeutic intervention. Only one survivor was reported following implantable cardioverter-defibrillator (ICD) extraction and voriconazole treatment. These findings underscore the insidious onset, diagnostic challenges, frequent therapeutic delays, and extremely high mortality associated with this infection.

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Publication Details

Journal
Journal of Cardiothoracic Surgery
Published
2026-03-02
DOI
https://doi.org/10.1186/s13019-026-03946-9
Primary Topic
Actinomycetales infections and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Scedosporium apiospermum endocarditis in an immunocompetent patient: a case report and literature review

Jingjing Zhang, Dandan Liu, Qingbin Zhang, Lei Li et al.
Journal of Cardiothoracic Surgery
Actinomycetales infections and treatment
article

Scedosporium apiospermum endocarditis in an immunocompetent patient: a case report and literature review

Jingjing Zhang, Dandan Liu, Qingbin Zhang, Lei Li, Wenqing Sun
article en

Abstract

S. apiospermum endocarditis carries a grave prognosis. Among 18 reviewed articals, 19 patients succumbed to the infection, 7 of whom were diagnosed postmortem, precluding therapeutic intervention. Only one survivor was reported following implantable cardioverter-defibrillator (ICD) extraction and voriconazole treatment. These findings underscore the insidious onset, diagnostic challenges, frequent therapeutic delays, and extremely high mortality associated with this infection.

Journal of Cardiothoracic Surgery
Shandong University (CN), Shandong Provincial QianFoShan Hospital (CN), Shandong First Medical University (CN)
Zero hunger
Openalex Percentile: Top 43%
Actinomycetales infections and treatment
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