Scedosporium apiospermum endocarditis in an immunocompetent patient: a case report and literature review
S. apiospermum endocarditis carries a grave prognosis. Among 18 reviewed articals, 19 patients succumbed to the infection, 7 of whom were diagnosed postmortem, precluding therapeutic intervention. Only one survivor was reported following implantable cardioverter-defibrillator (ICD) extraction and voriconazole treatment. These findings underscore the insidious onset, diagnostic challenges, frequent therapeutic delays, and extremely high mortality associated with this infection.
Authors
- Jingjing Zhang
- Dandan Liu
- Qingbin Zhang
- Lei Li
- Wenqing Sun
Institutions
- Shandong University (CN)
- Shandong Provincial QianFoShan Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Journal of Cardiothoracic Surgery
- Published
- 2026-03-02
- DOI
- https://doi.org/10.1186/s13019-026-03946-9
- Primary Topic
- Actinomycetales infections and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00