KPC-33 and ompK37 mutations: Unraveling the mechanism of ceftazidime/avibactam resistance in ST11 carbapenem-resistant Klebsiella pneumoniae
blaKPC-33 coupled with OmpK37 alterations underpins dual resistance to ceftazidime-avibactam and carbapenems in ST11 CRKP, underscoring the need for genomic surveillance and rapid detection of this resistance mechanism.
Authors
- L Ye
- Haiquan Kang
- Fei Jiang
- Jinfeng Xu
- Jingfang Sun
- Shulong Zhao
- Shuang Song
Institutions
- Xuzhou Medical College (CN)
- Xinjiang Uygur Autonomous Region Disease Prevention and Control Center (CN)
- Jiangsu Provincial Center for Disease Control and Prevention (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2026-03-02
- DOI
- https://doi.org/10.1371/journal.pone.0342729
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00