Dynamic changes and prognostic utility of procalcitonin, D-dimer, and lactate dehydrogenase in patients with sepsis and septic shock

PCT, D-D, and LDH are valuable biomarkers for stratifying disease severity and predicting clinical outcomes in patients with sepsis. Admission levels of these biomarkers were independently associated with the development of septic shock, and their dynamic changes provided additional prognostic information.

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Publication Details

Journal
Frontiers in Medicine
Published
2026-03-02
DOI
https://doi.org/10.3389/fmed.2026.1771448
Primary Topic
Sepsis Diagnosis and Treatment
Type
article
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article

Dynamic changes and prognostic utility of procalcitonin, D-dimer, and lactate dehydrogenase in patients with sepsis and septic shock

H. Wu, Weimin Song, Hongmei Ding, Zhen Ren et al.
Frontiers in Medicine
Sepsis Diagnosis and Treatment
article

Dynamic changes and prognostic utility of procalcitonin, D-dimer, and lactate dehydrogenase in patients with sepsis and septic shock

H. Wu, Weimin Song, Hongmei Ding, Zhen Ren, Qiuxia Ge
article en

Abstract

PCT, D-D, and LDH are valuable biomarkers for stratifying disease severity and predicting clinical outcomes in patients with sepsis. Admission levels of these biomarkers were independently associated with the development of septic shock, and their dynamic changes provided additional prognostic information.

Frontiers in MedicineVol. 13
National Clinical Research (US), Jiangsu Province Hospital (CN), Nanjing Medical University (CN)
No poverty
Openalex Percentile: Top 38%
Sepsis Diagnosis and Treatment
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