Odontogenic Brain Abscess in a Hereditary Haemorrhagic Telangiectasia (HHT) Patient: Case Report with a Comprehensive Literature Review

This is the first report of <i>Ca. Saccharibacteria</i> oral taxon 488 in a clinical sample and the first detection of any species from this phylum in a brain abscess, co-detected with <i>A. propionica,</i> consistent with its obligate epibiotic lifestyle. Our findings broaden the known microbial diversity associated with odontogenic brain abscesses and underscore the value of 16S rDNA NGS in characterising polymicrobial infections, particularly when fastidious or uncultivable organisms are involved.

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Publication Details

Journal
Tropical Medicine and Infectious Disease
Published
2026-03-02
DOI
https://doi.org/10.3390/tropicalmed11030067
Primary Topic
Otolaryngology and Infectious Diseases
Type
article
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article

Odontogenic Brain Abscess in a Hereditary Haemorrhagic Telangiectasia (HHT) Patient: Case Report with a Comprehensive Literature Review

Øyvind Kommedal, Joakim Stray Andreassen, Pontus Westerström, Jan Egil Afset et al.
Tropical Medicine and Infectious Disease
Otolaryngology and Infectious Diseases
article

Odontogenic Brain Abscess in a Hereditary Haemorrhagic Telangiectasia (HHT) Patient: Case Report with a Comprehensive Literature Review

Øyvind Kommedal, Joakim Stray Andreassen, Pontus Westerström, Jan Egil Afset, Joanna Malgorzata Bivand, Birgitta Ehrnström
article en

Abstract

This is the first report of <i>Ca. Saccharibacteria</i> oral taxon 488 in a clinical sample and the first detection of any species from this phylum in a brain abscess, co-detected with <i>A. propionica,</i> consistent with its obligate epibiotic lifestyle. Our findings broaden the known microbial diversity associated with odontogenic brain abscesses and underscore the value of 16S rDNA NGS in characterising polymicrobial infections, particularly when fastidious or uncultivable organisms are involved.

Tropical Medicine and Infectious DiseaseVol. 11(3)
Norwegian University of Science and Technology (NO), Haukeland University Hospital (NO), St Olav's University Hospital (NO), University of Bergen (NO)
Openalex Percentile: Top 38%
Otolaryngology and Infectious Diseases
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Odontogenic Brain Abscess in a Hereditary Haemorrhagic Telangiectasia (HHT) Patient: Case Report with a Comprehensive Literature Review — Øyvind Kommedal, Joakim Stray Andreassen, et al. · Tropical Medicine and Infectious Disease (2026) | TGRS Research Map | TGRS