Visnagin Protects Against Lipopolysaccharide-Induced Acute Kidney Injury by Inhibiting Oxidative Stress and Reducing Ferroptosis

Visnagin exerts protective actions through both modulation of Akt/Nrf2 signaling ACSL4/TfR1 signaling and direct free radical scavenging. These findings underscore visnagin's potential as a multitarget therapeutic agent for SA-AKI.

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Publication Details

Journal
International Journal of Medical Sciences
Published
2026-02-18
DOI
https://doi.org/10.7150/ijms.125642
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00

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article

Visnagin Protects Against Lipopolysaccharide-Induced Acute Kidney Injury by Inhibiting Oxidative Stress and Reducing Ferroptosis

Shengwen Wu, Yu-Hsiang Kuan, Chien-Ying Lee, Ching-Chi Tseng et al.
International Journal of Medical Sciences
Ferroptosis and cancer prognosis
article

Visnagin Protects Against Lipopolysaccharide-Induced Acute Kidney Injury by Inhibiting Oxidative Stress and Reducing Ferroptosis

Shengwen Wu, Yu-Hsiang Kuan, Chien-Ying Lee, Ching-Chi Tseng, Yin-Che Lu, Wen-Ying Chen, Shiuan-Shinn Lee, Chen-Yu Chiang, Chun-Jung Chen
article en

Abstract

Visnagin exerts protective actions through both modulation of Akt/Nrf2 signaling ACSL4/TfR1 signaling and direct free radical scavenging. These findings underscore visnagin's potential as a multitarget therapeutic agent for SA-AKI.

International Journal of Medical SciencesVol. 23(3)
National Chung Hsing University (TW), Taichung Veterans General Hospital (TW), Chung Shan Medical University Hospital (TW), Chia-Yi Christian Hospital (TW), Aesthetic Surgery Center (US), Yamato Municipal Hospital (JP), Chung Shan Medical University (TW)
Chung Shan Medical University, Ditmanson Medical Foundation Chia-Yi Christian Hospital, National Science and Technology Council, Chung Shan Medical University Hospital
Openalex Percentile: Top 37%
Ferroptosis and cancer prognosis
DOIOpen Access PDFOpenAlex
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Visnagin Protects Against Lipopolysaccharide-Induced Acute Kidney Injury by Inhibiting Oxidative Stress and Reducing Ferroptosis — Shengwen Wu, Yu-Hsiang Kuan, et al. · International Journal of Medical Sciences (2026) | TGRS Research Map | TGRS