Single-cell transcriptomics reveals heterogeneous neutrophil populations and diagnostic biomarkers in atherosclerosis
Our findings uncover the previously unrecognized heterogeneity of neutrophils in atherosclerosis and identify four key genes as promising diagnostic markers and therapeutic targets. These findings provide new insights into the pathogenesis of atherosclerosis and provide a theoretical basis for developing targeted therapies against this devastating disease.
Authors
- Quanli Qiu
- Qiang Fu (ORCID: https://orcid.org/0000-0002-4523-608X)
- Qiyu Sun
- J L Yang
- Xiaowen Ma
- Yuefeng Cai
- Zhenzhen Cui
- Ping Wang
- Min Li
Institutions
- University of Illinois Urbana-Champaign (US)
- 82th Hospital of Pla (CN)
- Jinzhou Medical University (CN)
Publication Details
- Journal
- Frontiers in Physiology
- Published
- 2026-03-02
- DOI
- https://doi.org/10.3389/fphys.2026.1704443
- Primary Topic
- Single-cell and spatial transcriptomics
- Type
- article
- Field-Weighted Citation Impact
- 0.00