AI-driven hybrid metaheuristic neural network approaches for medical diagnostics

In recent years, metaheuristic algorithms have gained prominence as powerful computational techniques for solving complex optimization problems across various domains, including healthcare. Their ability to effectively explore vast solution spaces enables them to identify optimal or near-optimal solutions to challenging problems. Despite their growing importance, metaheuristic algorithms, inspired by natural and human problem-solving strategies, are increasingly applied in healthcare to address complex optimization challenges such as diagnosis, treatment planning, and resource allocation. But traditional ML models often face problems like getting stuck in training, taking too much time to compute, and not balancing exploration and exploitation properly. These issues make them less effective for solving complex medical classification problems. To overcome these limitations, this study introduces new hybrid metaheuristic models such as Ropalidia Marginata (RM) hybrid with various metaheuristic algorithms such as Ant Colony Optimization (ACO), particle swarm optimization (PSO), Firefly, Artificial Bee Colony (ABC), Grey Wolf Optimizer (GWO), Differential Evolution (DE), and Bat Algorithm. Further all these hybrid metaheuristic algorithms are combined with a Feedforward Neural Network (FFNN) to train the network more efficiently. The proposed method uses the dominance-based behavior of RM wasp to improve the global search ability, is stable during learning, and improves classification accuracy. The performance of proposed frameworks is to check against several start of the art models on three critical medical datasets such as breast cancer, diabetes, and heart disease. The results showed that proposed models gave better results than the traditional algorithms in terms of accuracy, mean squared error (MSE), standard deviation (SD), and AUC-ROC.

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Publication Details

Journal
Systems and Soft Computing
Published
2026-03-02
DOI
https://doi.org/10.1016/j.sasc.2026.200471
Primary Topic
Artificial Intelligence in Healthcare
Type
article
Field-Weighted Citation Impact
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article

AI-driven hybrid metaheuristic neural network approaches for medical diagnostics

Dzati Athiar Ramli, Md Abdullah Saeed Khan, Maria Ali
Systems and Soft Computing
Artificial Intelligence in Healthcare
article

AI-driven hybrid metaheuristic neural network approaches for medical diagnostics

Dzati Athiar Ramli, Md Abdullah Saeed Khan, Maria Ali
article en

Abstract

In recent years, metaheuristic algorithms have gained prominence as powerful computational techniques for solving complex optimization problems across various domains, including healthcare. Their ability to effectively explore vast solution spaces enables them to identify optimal or near-optimal solutions to challenging problems. Despite their growing importance, metaheuristic algorithms, inspired by natural and human problem-solving strategies, are increasingly applied in healthcare to address complex optimization challenges such as diagnosis, treatment planning, and resource allocation. But traditional ML models often face problems like getting stuck in training, taking too much time to compute, and not balancing exploration and exploitation properly. These issues make them less effective for solving complex medical classification problems. To overcome these limitations, this study introduces new hybrid metaheuristic models such as Ropalidia Marginata (RM) hybrid with various metaheuristic algorithms such as Ant Colony Optimization (ACO), particle swarm optimization (PSO), Firefly, Artificial Bee Colony (ABC), Grey Wolf Optimizer (GWO), Differential Evolution (DE), and Bat Algorithm. Further all these hybrid metaheuristic algorithms are combined with a Feedforward Neural Network (FFNN) to train the network more efficiently. The proposed method uses the dominance-based behavior of RM wasp to improve the global search ability, is stable during learning, and improves classification accuracy. The performance of proposed frameworks is to check against several start of the art models on three critical medical datasets such as breast cancer, diabetes, and heart disease. The results showed that proposed models gave better results than the traditional algorithms in terms of accuracy, mean squared error (MSE), standard deviation (SD), and AUC-ROC.

Systems and Soft ComputingVol. 8
Openalex Percentile: Top 38%
Artificial Intelligence in Healthcare
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AI-driven hybrid metaheuristic neural network approaches for medical diagnostics — Dzati Athiar Ramli, Md Abdullah Saeed Khan, et al. · Systems and Soft Computing (2026) | TGRS Research Map | TGRS