Outcomes of patients with oral cavity squamous cell carcinomas with perineural invasion treated with adjuvant intensity modulated radiation therapy (IMRT)
PNI is an intermediate risk factor found to be a significant negative independent prognostic indicator in our patient cohort, which can help guide clinical decision-making for patients with OCSSC.
Authors
- Zahra Rahman Kelly
- Dan Paul Zandberg (ORCID: https://orcid.org/0000-0002-1002-8301)
- Phillip M. Pifer (ORCID: https://orcid.org/0000-0002-2810-2610)
- Uzoma K. Iheagwara
- Shaum Sridharan (ORCID: https://orcid.org/0000-0001-6049-1508)
- Kasey R. Cargill (ORCID: https://orcid.org/0000-0003-3082-1937)
- Mark Kubik (ORCID: https://orcid.org/0000-0002-4832-8422)
- Raja R. Seethala
- Umamaheswar Duvvuri
- Heath D. Skinner
- Robert L. Ferris
- John A. Vargo
- Jose Zevallos
- Seungwon Kim
- Yvonne M. Mowery
Institutions
- West Virginia University (US)
- West Virginia University Hospitals (US)
- UPMC Hillman Cancer Center (US)
- University of Pittsburgh Medical Center (US)
Publication Details
- Journal
- Clinical and Translational Radiation Oncology
- Published
- 2026-03-02
- DOI
- https://doi.org/10.1016/j.ctro.2026.101141
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Cancer Institute