UBA1 promotes cardiac hypertrophy by suppressing autophagy via targeting ATG5 for ubiquitination
UBA1 regulates cardiac hypertrophy through suppression of ATG5-mediated autophagy and propose UBA1 as a therapeutic target for hypertrophic cardiomyopathy.
Authors
- Hai-Lian Bi (ORCID: https://orcid.org/0000-0002-9825-6973)
- Jiaxin Li (ORCID: https://orcid.org/0000-0003-3821-893X)
- Hui-Hua Li
- Wei-Jia Yu (ORCID: https://orcid.org/0000-0002-7331-5500)
- Shujing Liu
- W. Jiang
Institutions
- Dalian Medical University (CN)
- First Affiliated Hospital of Dalian Medical University (CN)
Publication Details
- Journal
- Cell Communication and Signaling
- Published
- 2026-03-02
- DOI
- https://doi.org/10.1186/s12964-026-02761-y
- Primary Topic
- Cardiomyopathy and Myosin Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00