Multifocality as a marker of aggressiveness in medullary thyroid carcinoma: a retrospective cohort analysis of lymph node metastasis and recurrence
Multifocal MTC exhibits aggressive behavior with high LNM and recurrence risks, driven by the number of tumor foci, demonstrating a dose-response relationship. These findings support incorporating multifocality into risk stratification for optimized management.
Authors
- Ziyi Chen (ORCID: https://orcid.org/0000-0003-1395-8069)
- Jing Yang (ORCID: https://orcid.org/0000-0001-9147-6415)
- Yidan Lu (ORCID: https://orcid.org/0000-0001-7476-2911)
- Di Ou
- Na Feng (ORCID: https://orcid.org/0000-0001-6205-1960)
- Zhiyan Jin
- Lingyan Zhou
- Jincao Yao
- Dong Xu
- Tian Jiang
- Chen Yang
- Liyu Chen
Institutions
- Wenzhou Medical University (CN)
- Zhejiang Cancer Hospital (CN)
- Zhejiang Academy of Social Sciences (CN)
- Zhejiang Lab (CN)
- Taizhou Central Hospital (CN)
- Zhejiang Taizhou Hospital (CN)
Publication Details
- Journal
- The Oncologist
- Published
- 2026-02-26
- DOI
- https://doi.org/10.1093/oncolo/oyag065
- Primary Topic
- Thyroid Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00