Using Local sIgE Threshold to Refine the Diagnosis of Local Allergic Rhinitis

A local sIgE threshold reliably identifies an immunologically distinct LAR endotype, aligning diagnosis with its type 2 pathophysiology. This biomarker-driven approach offers a precise tool to refine diagnostic algorithms and improve patient selection for targeted therapies.

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Publication Details

Journal
International Forum of Allergy & Rhinology
Published
2026-03-02
DOI
https://doi.org/10.1002/alr.70131
Primary Topic
Allergic Rhinitis and Sensitization
Type
article
Field-Weighted Citation Impact
0.00
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article

Using Local sIgE Threshold to Refine the Diagnosis of Local Allergic Rhinitis

Lin Xi, Xi Zhang, Jingyun Li, Zengxiao Zhang et al.
International Forum of Allergy & Rhinology
Allergic Rhinitis and Sensitization
article

Using Local sIgE Threshold to Refine the Diagnosis of Local Allergic Rhinitis

Lin Xi, Xi Zhang, Jingyun Li, Zengxiao Zhang, Yu Zhang, Yu Song, Yuan Zhang, Luo Zhang, Yu Zhang
article en

Abstract

A local sIgE threshold reliably identifies an immunologically distinct LAR endotype, aligning diagnosis with its type 2 pathophysiology. This biomarker-driven approach offers a precise tool to refine diagnostic algorithms and improve patient selection for targeted therapies.

International Forum of Allergy & Rhinology
Beijing Tongren Hospital (CN), Capital Medical University (CN), Beijing Municipal Education Commission (CN)
Good health and well-being
Openalex Percentile: Top 32%
Allergic Rhinitis and Sensitization
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