Machine learning: predicting lymph node metastasis around the entrance point to the recurrent laryngeal nerve in cN0 papillary thyroid carcinoma

The interpretable ML model developed in this study, leveraging the RF, provides a reliable tool for preoperative and intraoperative prediction of LN-epRLN metastasis in cN0 PTC patients. This approach has the potential to guide individualized surgical planning, optimizing the balance between oncological resection completeness and functional preservation.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2026-03-02
DOI
https://doi.org/10.3389/fendo.2026.1721148
Primary Topic
Thyroid Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Machine learning: predicting lymph node metastasis around the entrance point to the recurrent laryngeal nerve in cN0 papillary thyroid carcinoma

Xinglin Su, Ying Deng, Chang Deng, Q. Xiao et al.
Frontiers in Endocrinology
Thyroid Cancer Diagnosis and Treatment
article

Machine learning: predicting lymph node metastasis around the entrance point to the recurrent laryngeal nerve in cN0 papillary thyroid carcinoma

Xinglin Su, Ying Deng, Chang Deng, Q. Xiao, Jie Peng, Jing Zhou
article en

Abstract

The interpretable ML model developed in this study, leveraging the RF, provides a reliable tool for preoperative and intraoperative prediction of LN-epRLN metastasis in cN0 PTC patients. This approach has the potential to guide individualized surgical planning, optimizing the balance between oncological resection completeness and functional preservation.

Frontiers in EndocrinologyVol. 17
The Affiliated Yongchuan Hospital of Chongqing Medical University (CN), Seventh People's Hospital of Shanghai (CN), Children's Hospital of Chongqing Medical University (CN), Chongqing Medical University (CN)
Chongqing Municipal Health Commission, Bethune Charitable Foundation, Chongqing Municipal Education Commission, Centre Scientifique et Technique du Bâtiment
Openalex Percentile: Top 38%
Thyroid Cancer Diagnosis and Treatment
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Machine learning: predicting lymph node metastasis around the entrance point to the recurrent laryngeal nerve in cN0 papillary thyroid carcinoma — Xinglin Su, Ying Deng, et al. · Frontiers in Endocrinology (2026) | TGRS Research Map | TGRS