Efficacy and Safety of Belantamab Mafodotin with Bortezomib Plus Dexamethasone in Patients with Relapsed/Refractory Multiple Myeloma: the DREAMM-6 Arm B Trial

BVd demonstrated manageable safety and clinical activity across all dosing cohorts in heavily pretreated RRMM, supporting the 2.5 mg/kg Q3W dose.

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Publication Details

Journal
Clinical Cancer Research
Published
2026-03-02
DOI
https://doi.org/10.1158/1078-0432.ccr-25-3216
Primary Topic
Multiple Myeloma Research and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Efficacy and Safety of Belantamab Mafodotin with Bortezomib Plus Dexamethasone in Patients with Relapsed/Refractory Multiple Myeloma: the DREAMM-6 Arm B Trial

Astrid McKeown, Ravi S. Kasinathan, Amit Khot, N. Patel et al.
Clinical Cancer Research
Multiple Myeloma Research and Treatments
article

Efficacy and Safety of Belantamab Mafodotin with Bortezomib Plus Dexamethasone in Patients with Relapsed/Refractory Multiple Myeloma: the DREAMM-6 Arm B Trial

Astrid McKeown, Ravi S. Kasinathan, Amit Khot, N. Patel, J. Opalinska, Mehreen Shaikh, Rachel Rogers, Bradley Augustson, Paul Cannell, Andrew Spencer, Sumita Roy-Ghanta, Keith Stockerl-Goldstein, Amy Curry, Fernando Carreno, Hang Quach, Ajay Nooka, Rakesh Popat
article en

Abstract

BVd demonstrated manageable safety and clinical activity across all dosing cohorts in heavily pretreated RRMM, supporting the 2.5 mg/kg Q3W dose.

Clinical Cancer Research
University College London Hospitals NHS Foundation Trust (GB), Emory University (US), GlaxoSmithKline (United Kingdom) (GB), Washington University in St. Louis (US), Age UK (GB), Peter MacCallum Cancer Centre (AU), Fiona Stanley Hospital (AU), Sir Charles Gairdner Hospital (AU), National Institute for Health and Care Research (GB), St Vincent's Hospital Melbourne (AU), GlaxoSmithKline (United States) (US), GlaxoSmithKline (Poland) (PL), GlaxoSmithKline (Germany) (DE), University College London (GB), Monash University (AU)
Seagen
Good health and well-being
Openalex Percentile: Top 38%
Multiple Myeloma Research and Treatments
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