High COMP expression promotes tumor cell proliferation and migration of rectal cancer, contributing to unfavorable prognosis and suppressive immune microenvironment
Collectively, significant higher COMP expression was noticed in public RC cohorts and RC cells, and si-COMP obviously inhibited the cell viability, migration, and invasion, implying its pathogenic role in RC.
Authors
- Jia Hao (ORCID: https://orcid.org/0000-0001-9836-9014)
- Jin Shang (ORCID: https://orcid.org/0000-0003-0556-8722)
- De-Zhi Yang
- Dong V Wang
- Wan-Jun Sheng
Institutions
- Hebei Medical University (CN)
- Fourth Hospital of Hebei Medical University (CN)
- Xingtai People's Hospital (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2026-03-02
- DOI
- https://doi.org/10.1007/s12672-026-04675-0
- Primary Topic
- interferon and immune responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00