Impact of Alkaline Phosphatase Normalization on Complication-Free Survival in Primary Biliary Cholangitis
Achieving normal ALP and TB ≤0.6xULN is associated with significantly improved complication-free survival, particularly in high-risk patients. These findings highlight the potential of biochemical thresholds as a meaningful therapeutic goal in PBC management.
Authors
- Marlyn J. Mayo (ORCID: https://orcid.org/0000-0002-4874-7010)
- A. Nagarjuna Reddy
- C Levy
- Andrea R. Mospan (ORCID: https://orcid.org/0000-0002-3419-8276)
- Raymond A. Rubin (ORCID: https://orcid.org/0000-0002-0536-7253)
- A. B. GOEL
- Hany Elbeshbeshy
- Adrielly Martins (ORCID: https://orcid.org/0000-0002-2653-2238)
- Mark Wong
- Elizabeth J. Carey
- Christopher L. Bowlus
- Michael Weiss
- On behalf of the OCEAN-TAVI investigators
Institutions
- Target (United States) (US)
- University of Miami (US)
- Virginia Commonwealth University (US)
- Clearwater Christian College (US)
- Piedmont Atlanta Hospital (US)
- Banner - University Medical Center Phoenix (US)
- Mayo Clinic in Arizona (US)
- Clinical Research of West Florida (US)
- Saint Louis University (US)
- University of California, Davis (US)
- The University of Texas Southwestern Medical Center (US)
- Stanford University (US)
Publication Details
- Journal
- The American Journal of Gastroenterology
- Published
- 2026-03-02
- DOI
- https://doi.org/10.14309/ajg.0000000000003973
- Primary Topic
- Liver Diseases and Immunity
- Type
- article
- Field-Weighted Citation Impact
- 0.00