Vessel-specific perivascular fat attenuation index derived from AI-CCTA and its association with impaired coronary flow reserve in patients with INOCA

FAI is independently associated with vessel-level CFR impairment in INOCA. The combined model demonstrates potential but requires external validation. The observed inverse spatial and functional relationship between CACS and FAI may reflect different stages or patterns of coronary atherosclerosis in non-obstructive CAD, warranting further investigation.