Decoding liver injury in cystic fibrosis: How to tell drug-induced liver injury from cystic fibrosis liver disease
Early recognition and differentiation between DILI and underlying CFLD are essential for optimizing therapy, preserving liver function, and guiding long-term management in patients with CF. As CFTR modulators become the cornerstone of CF management, vigilance for hepatotoxicity is critical. A multidisciplinary approach involving hepatology and CF care teams is recommended.
Authors
- Benyam D. Addissie
- Patrick Twohig (ORCID: https://orcid.org/0000-0002-5423-8749)
- Joshua Rosario
- Nicholas Lim (ORCID: https://orcid.org/0000-0001-9261-7726)
- Gopal Ramaraju
- Junseo Lee
- Michael R Narkewicz
- Ava Wexler
- William Zhuang
- Anuroop Yekula
- Ashwath Elangovan
- Philomena Burger
Institutions
- University of Rochester Medical Center (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- World Journal of Gastroenterology
- Published
- 2026-03-02
- DOI
- https://doi.org/10.3748/wjg.v32.i10.114946
- Primary Topic
- Cystic Fibrosis Research Advances
- Type
- article
- Field-Weighted Citation Impact
- 0.00