Unveiling the Small Molecules Binding Site of CD36 Cell Surface Receptor Through Docking and Molecular Dynamics Simulations
This study highlights critical residues and structural features involved in ligand recognition by CD36. The identification of the SMAC and its role in modulating LCFA uptake provides promising insights for the development of therapeutic agents targeting CD36-related pathologies, including cancer, diabetes, and metabolic disorders.
Authors
- José Correa‐Basurto (ORCID: https://orcid.org/0000-0002-4973-5265)
- David Méndez-Luna (ORCID: https://orcid.org/0000-0002-2488-7916)
- Vicente Sandoval-Herrera (ORCID: https://orcid.org/0000-0003-4984-0644)
- Rosa Salgado-Brito
- José-Rubén García-Sánchez
- Sergio-Roberto Zamudio-Hernández
- Naomi Montes-Mondragón
- Martiniano Bello
Institutions
- Universidad Insurgentes (MX)
- Instituto Politécnico Nacional (MX)
Publication Details
- Journal
- Current Medicinal Chemistry
- Published
- 2026-02-26
- DOI
- https://doi.org/10.2174/0109298673413172251202110617
- Primary Topic
- Peroxisome Proliferator-Activated Receptors
- Type
- article
- Field-Weighted Citation Impact
- 0.00