MZB1 Drives Periodontitis via ER Stress-Mediated Inflammation and Osteogenic Differentiation

Targeting MZB1 represents a promising therapeutic strategy. Inhibiting MZB1 could alleviate ER stress, enhance bone regeneration, and restore periodontal tissue homeostasis, potentially leading to more effective and regenerative treatments for periodontitis.

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Publication Details

Journal
International Dental Journal
Published
2026-03-02
DOI
https://doi.org/10.1016/j.identj.2026.109452
Primary Topic
Oral microbiology and periodontitis research
Type
article
Field-Weighted Citation Impact
0.00
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article

MZB1 Drives Periodontitis via ER Stress-Mediated Inflammation and Osteogenic Differentiation

Qipeng Jiang, Qun Xiang, Xianmei Hu, Manjuan Chen et al.
International Dental Journal
Oral microbiology and periodontitis research
article

MZB1 Drives Periodontitis via ER Stress-Mediated Inflammation and Osteogenic Differentiation

Qipeng Jiang, Qun Xiang, Xianmei Hu, Manjuan Chen, Lei Wang (6656), Yang Zhao, Fei Ge
article en

Abstract

Targeting MZB1 represents a promising therapeutic strategy. Inhibiting MZB1 could alleviate ER stress, enhance bone regeneration, and restore periodontal tissue homeostasis, potentially leading to more effective and regenerative treatments for periodontitis.

International Dental JournalVol. 76(3)
Shanxi Medical University (CN), Stomatology Hospital (CN), Second Hospital of Shanxi Medical University (CN), Southern Medical University Shenzhen Hospital (CN), Shenzhen Entry-Exit Inspection and Quarantine Bureau (CN)
Openalex Percentile: Top 39%
Oral microbiology and periodontitis research
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