The dynamic changes of serum levels of PD-1/PD-L1 correlate with the therapeutic effectiveness of antibiotics in patients with sepsis

Serum sPD-1 and sPD-L1 levels are significantly elevated in Enterobacteriaceae sepsis and dynamically decreased in patients responding to therapy. These findings underscore their potential as valuable prognostic biomarkers for monitoring immune reconstitution and treatment efficacy.

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Publication Details

Journal
Bioanalysis
Published
2026-01-22
DOI
https://doi.org/10.1080/17576180.2026.2637733
Primary Topic
Inflammation biomarkers and pathways
Type
article
Field-Weighted Citation Impact
0.00
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article

The dynamic changes of serum levels of PD-1/PD-L1 correlate with the therapeutic effectiveness of antibiotics in patients with sepsis

Y F Li, Biran Ding, Yuanbao Xu, Lei Ye
Bioanalysis
Inflammation biomarkers and pathways
article

The dynamic changes of serum levels of PD-1/PD-L1 correlate with the therapeutic effectiveness of antibiotics in patients with sepsis

Y F Li, Biran Ding, Yuanbao Xu, Lei Ye
article en

Abstract

Serum sPD-1 and sPD-L1 levels are significantly elevated in Enterobacteriaceae sepsis and dynamically decreased in patients responding to therapy. These findings underscore their potential as valuable prognostic biomarkers for monitoring immune reconstitution and treatment efficacy.

BioanalysisVol. 18(2)
Anhui Medical University (CN), First Affiliated Hospital of Anhui Medical University (CN)
Good health and well-being
Openalex Percentile: Top 38%
Inflammation biomarkers and pathways
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