Günübirlik Jinekolojik Girişimlerde Farklı Anestezik Ajanların Hemodinami, Derlenme ve Postoperative Kognitif Fonksiyonlar Üzerine Etkilerinin Karşılaştırılması

ABSTRACTObjective:The aim of this study was to compare the effects of three different intravenous induction agents—propofol, etomidate, and thiopental—on hemodynamic parameters, recovery times, and postoperative cognitive functions in patients undergoing short-duration ambulatory vaginal gynecologic procedures.Methods:This prospective observational study was conducted at the Gynecology and Obstetrics Operating Room of Istanbul Training and Research Hospital between March and May 2010. A total of 120 patients, aged 25–75 years and classified as ASA physical status I–II, were included. Patients were randomly divided into three groups: Group P (Propofol 2 mg·kg⁻¹), Group E (Etomidate 0.3 mg·kg⁻¹), and Group T (Thiopental 5–7 mg·kg⁻¹). All groups received fentanyl 1.5 µg·kg⁻¹ for analgesia. Hemodynamic parameters, recovery times, Ramsey Sedation Scores, and Mini-Mental Test (MMT) scores were recorded and analyzed.Results:In Group P, significant decreases in systolic and diastolic blood pressure were observed following induction (p