Real-world outcomes of encorafenib, cetuximab ± binimetinib for <i>BRAF</i> ‑mutated metastatic colorectal cancer: the BEETS (JACCRO CC‑18) study
In real-world clinical practice, triplet and doublet therapies showed comparable survival outcomes, consistent with the BEACON trial. Triplet therapy may provide potential clinical benefit in patients with poor PFs.
Authors
- Kotoe Oshima (ORCID: https://orcid.org/0000-0003-1491-9811)
- Chiaki Inagaki (ORCID: https://orcid.org/0000-0003-1282-232X)
- Yusuke Suwa
- Tomomi Kashiwada (ORCID: https://orcid.org/0000-0001-8076-5545)
- Daisuke Kotani (ORCID: https://orcid.org/0000-0002-4196-555X)
- Hidekazu Kuramochi (ORCID: https://orcid.org/0000-0003-0875-7393)
- Tadamichi Denda (ORCID: https://orcid.org/0000-0003-2570-9692)
- Akinori Sugaya
- Satoshi Yuki (ORCID: https://orcid.org/0000-0002-2039-3062)
- Takashi Ohta
- Yoshiaki Mihara
- W. Ichikawa
- Eisuke Inoue
- Manabu Shiozawa
- Yu Sunakawa
- Masashi Fujii
- Kei Muro
Institutions
- SHOWA Medical University (JP)
- St. Marianna University School of Medicine (JP)
- Kagawa University (JP)
- NTT Medical Center (JP)
- Yokohama City University Medical Center (JP)
- Kanagawa Prefectural Hospital Organization (JP)
- Shizuoka Cancer Center (JP)
- Saga-Ken Medical Centre Koseikan (JP)
- Kansai Rosai Hospital (JP)
- Kindai University Sakai Hospital (JP)
- Chiba Cancer Center (JP)
- Aichi Cancer Center (JP)
- Kagawa University Hospital (JP)
- Ibaraki Prefectural Central Hospital (JP)
- Hokkaido University Hospital (JP)
- National Cancer Center Hospital East (JP)
- Japan Clinical Cancer Research Organization (JP)
- SHOWA Medical University Fujigaoka Hospital (JP)
- SHOWA Medical University Hospital (JP)
- Yokohama City University (JP)
Publication Details
- Journal
- The Oncologist
- Published
- 2026-02-25
- DOI
- https://doi.org/10.1093/oncolo/oyag068
- Primary Topic
- Colorectal Cancer Treatments and Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00