Effects of Prostatic Arterial Embolization With α-Blocker for Advanced Age Benign Prostatic Hyperplasia

Background and Objective: There is no universally accepted understanding of the complex pathogenesis of Benign Prostatic Hyperplasia (BPH). Precision prostate artery embolization (PPAE) is performed under the guidance of digital subtraction angiography and can alleviate clinical symptoms caused by BPH. This research assessed the effectiveness of PPAE combined with highly specific α1 blockers for elderly BPH patients. Materials and Methods: The 144 elderly BPH patients were split into two groups: 80 for observation and 64 for control. The study treated all participants with α1 blockers, while the observation group additionally received precise prostatic artery embolization (PPAE). Changes in clinical symptoms before and after therapy were monitored.The statistical assessment was done by SPSS 22.00. Count data were reported as a percentage (%), while data were expressed as the Mean ± Standard Deviation (SD). The threshold of significance was p < 0.05. Results: The treatment led to a significantly greater overall effective rate in the observation group than in the control group (p < 0.05). Both groups had lower international prognostic scoring system (IPSS) and urinary symptom distress (BS) levels than before therapy (p < 0.05), with the observation group also having lower scores. After 2 weeks, 1 month, 6 months and 1 year of therapy, both groups saw substantial increases in Qmax, while the fraction of residual urine volume (RU), prostate volume (PV) and ischemia were reduced. The observation group improved more significantly than the control group. The observation group was considerably lower than the control group (p < 0.05). Conclusion: High selectivity α1-receptor blockers have good feasibility in the treatment of elderly BPH and combined with precise PAE can improve the treatment effect, with good safety and reliability.