Efficacy and Safety of Immune Checkpoint Inhibitors in Non-Small Cell Lung Cancer With Lymph Node Metastasis

In previously treated patients with unresectable NSCLC and lymph node metastasis, real-world evidence from this study suggests that pembrolizumab monotherapy offers superior efficacy and survival benefits compared with docetaxel chemotherapy. Moreover, the two therapies display distinct safety profiles, with ICI therapy associated with fewer severe hematologic toxicities.

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Publication Details

Journal
British Journal of Hospital Medicine
Published
2026-02-05
DOI
https://doi.org/10.31083/bjhm50722
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
0.00
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article

Efficacy and Safety of Immune Checkpoint Inhibitors in Non-Small Cell Lung Cancer With Lymph Node Metastasis

Liangliang Xue, Kai Ma, Ge Wang, Ru Ma et al.
British Journal of Hospital Medicine
Cancer Immunotherapy and Biomarkers
article

Efficacy and Safety of Immune Checkpoint Inhibitors in Non-Small Cell Lung Cancer With Lymph Node Metastasis

Liangliang Xue, Kai Ma, Ge Wang, Ru Ma, Wenhai Li
article en

Abstract

In previously treated patients with unresectable NSCLC and lymph node metastasis, real-world evidence from this study suggests that pembrolizumab monotherapy offers superior efficacy and survival benefits compared with docetaxel chemotherapy. Moreover, the two therapies display distinct safety profiles, with ICI therapy associated with fewer severe hematologic toxicities.

British Journal of Hospital MedicineVol. 87(2)
Medical Center Hospital (US), Second Affiliated Hospital of Xi'an Jiaotong University (CN)
Good health and well-being
Openalex Percentile: Top 37%
Cancer Immunotherapy and Biomarkers
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