Integrative Analysis of Glycine, Serine, and Threonine Metabolism and the Immune Microenvironment in Endometrial Cancer: A Prognostic Model and Metabolic-Immune Framework for Precision Oncology
This study developed a Gly/Ser/Thr pathway-based prognostic model for EC, based on the expression of MTHFD2, RPS6KA1, and CDKN2A as novel biomarkers. The resulting patient stratification framework holds significant clinical potential for guiding precise and personalized management of EC.
Authors
- Xite Lin (ORCID: https://orcid.org/0000-0003-2157-0574)
- Maotong Zhang (ORCID: https://orcid.org/0009-0008-3458-3685)
- Yashi Shi
- Xiaodan Mao
- Jingxuan Ye
- Pengming Sun
Institutions
- Fujian Medical University (CN)
- Fujian Women and Children Hospital (CN)
- Fuzhou Maternity and Child Health Care Hospital (CN)
Publication Details
- Journal
- Frontiers in Bioscience-Landmark
- Published
- 2026-02-11
- DOI
- https://doi.org/10.31083/fbl48779
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00