New phenotype and outcomes in connective tissue disease-associated pulmonary arterial hypertension: relevance of age-related comorbidities

Contemporary CTD-PAH patients included in REHAP are older and have a lower comorbidity burden than IPAH patients, while exhibiting similar survival rates up to 5 years. CKD is an independent prognostic factor in both aetiologies. CTD-PAH patients tend to receive a more conservative treatment approach.

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Publication Details

Journal
Lara D. Veeken
Published
2026-02-24
DOI
https://doi.org/10.1093/rheumatology/keag105
Primary Topic
Pulmonary Hypertension Research and Treatments
Type
article
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article

New phenotype and outcomes in connective tissue disease-associated pulmonary arterial hypertension: relevance of age-related comorbidities

Rafael Bravo Marqués, F Rivas-Ruiz, Isabel Blanco Vich, Pedro Antonio Chinchurreta Capote et al.
Lara D. Veeken
Pulmonary Hypertension Research and Treatments
article

New phenotype and outcomes in connective tissue disease-associated pulmonary arterial hypertension: relevance of age-related comorbidities

Rafael Bravo Marqués, F Rivas-Ruiz, Isabel Blanco Vich, Pedro Antonio Chinchurreta Capote, Pilar Escribano-subias, Víctor Becerra, Elías Ortiz, Andrés Tenes, Manuel Lopez-Meseguer, I Martin De Miguel, the REHAP investigators, Joan A Barberà
article en

Abstract

Contemporary CTD-PAH patients included in REHAP are older and have a lower comorbidity burden than IPAH patients, while exhibiting similar survival rates up to 5 years. CKD is an independent prognostic factor in both aetiologies. CTD-PAH patients tend to receive a more conservative treatment approach.

Lara D. VeekenVol. 65(3)
Universidad Complutense de Madrid (ES), Instituto Cajal (ES), Pulmonary Hypertension Association (US), Research Institute Hospital 12 de Octubre (ES), Hospital Costa del Sol (ES), Centro de Investigación en Red en Enfermedades Cardiovasculares (ES), Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (ES), Hospital Universitario 12 De Octubre (ES), Red de Investigación en Actividades Preventivas y Promoción de la Salud (ES), Centro de Investigación Biomédica en Red (ES), Instituto Ramón y Cajal de Investigación Sanitaria (ES), Vall d'Hebron Hospital Universitari (ES), ERN GUARD-Heart (NL), Hospital Clínico Universitario Virgen de la Victoria (ES), Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES), Hospital Universitario Ramón y Cajal (ES), Instituto de Investigación Biomédica de Málaga (ES)
Good health and well-being
Openalex Percentile: Top 39%
Pulmonary Hypertension Research and Treatments
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