WDR4 is a Potential Indicator of Clinical Diagnostics, Prognosis, and Immunotherapy in Hepatocellular Carcinoma (HCC)

<i>WDR4</i> shows elevated expression in HCC tissues and is associated with immune infiltration, establishing it as a prognostic biomarker in HCC. Furthermore, the positive correlation observed between <i>WDR4</i> and CD68, as well as PD-L1 (<i>CD274</i>), underscores its potential as a guiding factor in immunotherapeutic approaches for HCC.

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Publication Details

Journal
Frontiers in Bioscience-Landmark
Published
2026-02-09
DOI
https://doi.org/10.31083/fbl45764
Primary Topic
Peptidase Inhibition and Analysis
Type
article
Field-Weighted Citation Impact
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article

WDR4 is a Potential Indicator of Clinical Diagnostics, Prognosis, and Immunotherapy in Hepatocellular Carcinoma (HCC)

Mazaher Maghsoudloo, Junjiang FU, Liyao Yang, Jingjing Wang et al.
Frontiers in Bioscience-Landmark
Peptidase Inhibition and Analysis
article

WDR4 is a Potential Indicator of Clinical Diagnostics, Prognosis, and Immunotherapy in Hepatocellular Carcinoma (HCC)

Mazaher Maghsoudloo, Junjiang FU, Liyao Yang, Jingjing Wang, Juan Wang, Yao Zhang, Min Li, Shasha Fan
article en

Abstract

<i>WDR4</i> shows elevated expression in HCC tissues and is associated with immune infiltration, establishing it as a prognostic biomarker in HCC. Furthermore, the positive correlation observed between <i>WDR4</i> and CD68, as well as PD-L1 (<i>CD274</i>), underscores its potential as a guiding factor in immunotherapeutic approaches for HCC.

Frontiers in Bioscience-LandmarkVol. 31(2)
Central South University (CN), Hunan Normal University (CN), Southwest Medical University (CN), Second Xiangya Hospital of Central South University (CN)
Good health and well-being
Openalex Percentile: Top 38%
Peptidase Inhibition and Analysis
DOIOpen Access PDFOpenAlex
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