Targeting Tumor Necrosis Factor-α Mitigates Glucose Fluctuation-Induced Aortic Valve Fibrosis: Insights From Diabetic Rat Models

Targeting TNF-α may serve as a potential therapeutic target to mitigate the progression of inflammation-induced aortic valve damage and fibrosis.

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Publication Details

Journal
Reviews in Cardiovascular Medicine
Published
2026-02-13
DOI
https://doi.org/10.31083/rcm42804
Primary Topic
Cardiac Valve Diseases and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Targeting Tumor Necrosis Factor-α Mitigates Glucose Fluctuation-Induced Aortic Valve Fibrosis: Insights From Diabetic Rat Models

Xiaosong Rong, Huiping Chen, Yu-Jia Chen, Ku-Lin Li et al.
Reviews in Cardiovascular Medicine
Cardiac Valve Diseases and Treatments
article

Targeting Tumor Necrosis Factor-α Mitigates Glucose Fluctuation-Induced Aortic Valve Fibrosis: Insights From Diabetic Rat Models

Xiaosong Rong, Huiping Chen, Yu-Jia Chen, Ku-Lin Li, Chang Ying Zhang, Ru-Xing Wang, Feng Xiao
article en

Abstract

Targeting TNF-α may serve as a potential therapeutic target to mitigate the progression of inflammation-induced aortic valve damage and fibrosis.

Reviews in Cardiovascular MedicineVol. 27(2)
Nantong University (CN), Taizhou Second People's Hospital (CN), The Affiliated Taizhou People's Hospital of Nanjing Medical University (CN), Wuxi People's Hospital (CN), Nanjing Medical University (CN)
Good health and well-being
Openalex Percentile: Top 44%
Cardiac Valve Diseases and Treatments
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