Epidemio-clinical Study of Simple Malaria in Adults in the General Medicine Department of the Reference Health Center of Bamako Municipality III in 2023

<i>Introduction:</i> Malaria remains a major public health problem in Mali. This study aimed to analyze the epidemiological and clinical aspects of uncomplicated malaria cases in adults treated at the general medicine department of the Reference Health Center in Commune III of Bamako in 2023.<i> Methods:</i> This was a cross-sectional study conducted from July 1 to December 31, 2023. All patients aged 18 years or older with either clinically suspected or confirmed uncomplicated malaria-diagnosed through thick blood film, thin blood smear, or rapid diagnostic test (RDT)-were included. Data were gathered through a questionnaire and subsequently entered and analyzed with SPSS version 25. The national malaria control protocol served as a reference for evaluating prescriptions. <i>Results:</i> A total of 317 uncomplicated malaria cases were recorded among 7,584 admissions, accounting for 4.9%. The mean age was 34 ± 15 years, with a female predominance (63%). The main clinical signs were headache (86.12%), chills (49.53%), and fever (52.7%). Thick blood smears were performed in 94% of cases and were positive in 86.44%. Antimalarial treatment was primarily based on artemether/lumefantrine (60.88%). The treatment protocol was appropriate in 65% of prescriptions. Conclusion: Uncomplicated malaria remains prevalent among adults in Commune III. Strengthening preventive measures and adhering to the protocol remain essential to reduce morbidity and prevent severe forms of malaria.