Pressing Intervention Alleviates Pain in Rats With Myofascial Trigger Points via the TRPV1 Channel in Unmyelinated C-Type Sensory Nerve Fibers
Pressing intervention increases the mechanical pain threshold and improves soft tissue tension in rats with MTrPs. The underlying mechanism may be associated with alleviating local inflammation, modulating the TRPV1 channel in unmyelinated C-type sensory nerve fibers, and inhibiting TRPV1 expression, thereby reducing sensory nerve excitability.
Authors
- Xiaoxia Kuang
- Wu Li (ORCID: https://orcid.org/0000-0003-2258-4409)
- Piao Zhang (ORCID: https://orcid.org/0000-0002-8941-7042)
- Liya Tang
- Xinyue Lv
- Jiangshang Li
- Fei Liu
Institutions
- Hunan University of Traditional Chinese Medicine (CN)
- Second Affiliated Hospital of Hunan University of Traditional Chinese Medicine (CN)
- University of South China (CN)
Publication Details
- Journal
- Journal of Integrative Neuroscience
- Published
- 2026-02-26
- DOI
- https://doi.org/10.31083/jin46853
- Primary Topic
- Pain Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00