DNA copy number patterns reveal prognostic markers and elucidate mechanisms of evolution in IDH-mutant astrocytoma
Patients with hemizygous loss of CDKN2A/B, loss of PTEN, increased number of copy number alterations, specific chromosomal arm losses or rs55705857 germline risk allele have reduced overall survival.
Authors
- Terry C. Burns (ORCID: https://orcid.org/0000-0001-7633-3045)
- S. Kizilbash
- Shameel Shafqat (ORCID: https://orcid.org/0000-0001-7617-3678)
- C. Giannini
- Cristiane M. Ida (ORCID: https://orcid.org/0000-0003-2768-2913)
- Rachael A. Vaubel (ORCID: https://orcid.org/0000-0001-8842-5975)
- Kristen Drucker (ORCID: https://orcid.org/0000-0001-6244-5863)
- Aditya Raghunathan
- Ian F. Parney (ORCID: https://orcid.org/0000-0002-9702-8047)
- Muhammad Asad Maqbool (ORCID: https://orcid.org/0000-0003-2798-7725)
- Daniel H. Lachance (ORCID: https://orcid.org/0000-0002-5475-9931)
- Arijit Panda (ORCID: https://orcid.org/0000-0001-5156-6459)
- Matt Kosel
- Paul A Decker
- Thomas M Kollmeyer
- Milovan Suvakov
- Robert B Jenkins
- Jeanette E Eckel-Passow
Institutions
- Mayo Clinic (US)
- Mayo Clinic in Arizona (US)
- Mayo Clinic in Florida (US)
Publication Details
- Journal
- Neuro-Oncology
- Published
- 2026-01-28
- DOI
- https://doi.org/10.1093/neuonc/noag019
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00