Impact of Equisetum arvense (L.) extract content on the formulation of gels

Introduction. Equisetum arvense (L.) is generally used in traditional medicine as a therapeutic and pain reliever in wound, skin diseases, hair loss. Topical application of gels at pathological sites offer great advantage in a faster release of drug directly to site of action, independent of water solubility of the drug [1]. Materials and methods. Water extracts samples of horsetail stem were extracted by comparing raw materials and water with polyethylene glycol in a ratio of 1:100 and extraction in an ultrasonic bath for 30 minutes. The gels were prepared using methyl cellulose and hydroxypropyl cellulose as gelling agents, E. arvense (L.) extract 10% and 12% and distilled water. All the materials were mixed well and the resulting gels were left in the refrigerator overnight. The consistency factor of gels was measured using MCR102 rotary rheometer with plate-plate geometry and Peltier system. [...].