Automatic data processing and results overview during SFX experiments

Serial Femtosecond Crystallography (SFX). Crystallography at European X-ray free electron laser (XFEL): Photon pulses are bright enough to observe diffraction from extremely small crystals; Femtosecond duration of individual pulses; Sample gets destroyed shortly after diffraction; Experiments are performed serially with a continuously resupplied sample; Still images from the randomly oriented crystals; Goal - reconstruct the electron density distribution corresponding to the atomic structure.

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Publication Details

Journal
European XFEL Publication Database
Published
2025-05-13
Primary Topic
Enzyme Structure and Function
Type
article
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article

Automatic data processing and results overview during SFX experiments

Diogo V. M. Melo, James J. Wrigley, E. V. Sobolev, Thomas A. White et al.
European XFEL Publication Database
Enzyme Structure and Function
article

Automatic data processing and results overview during SFX experiments

Diogo V. M. Melo, James J. Wrigley, E. V. Sobolev, Thomas A. White, F Dall'Antonia, Cammille Carinan, Matheus C. Teodoro, Raphaël de Wijn, Robert Rosca, David Hammer, Danilo Enoque Ferreira de Lima, Luca Gelisio, Thomas Michelat, Oleksii Turkot
article en

Abstract

Serial Femtosecond Crystallography (SFX). Crystallography at European X-ray free electron laser (XFEL): Photon pulses are bright enough to observe diffraction from extremely small crystals; Femtosecond duration of individual pulses; Sample gets destroyed shortly after diffraction; Experiments are performed serially with a continuously resupplied sample; Still images from the randomly oriented crystals; Goal - reconstruct the electron density distribution corresponding to the atomic structure.

European XFEL Publication Database
Openalex Percentile: Top 44%
Enzyme Structure and Function
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