Correlation of kidney graft function with changes in T1 mapping on 3 Tesla magnetic resonance imaging

Background and Aim. This study investigates the ability of T1 mapping to detect microstructural changes in cadaveric kidneys during the early post- transplantation period using magnetic resonance imaging (MRI) (1). The aim is to compare the MRI characteristics of transplanted kidneys (kTx) with different creatinine clearance levels at 7-10 days post-transplantation against those of healthy kidneys. Materials and Methods. With institutional ethics approval, we conducted a prospective study at the Hospital of the Lithuanian University of Health Sciences, Kaunas Clinics, involving 34 kidney transplant recipients and a control group of 30 healthy individuals. MRI scans were performed using a 3T Siemens Skyra scanner (Table 1). Image analysis was conducted by radiologists and a nephrologist using Parametric MRI v1.2.31-b software (Figure 1). Graft function was classified as immediate (IGF), slow (SGF), or delayed (DGF) based on the classification by Isaac E. Hall et al. (2). Clinical and laboratory data are presented in Table 2. [...].