Type 2 diabetes mellitus and liver diseases: a phenome-wide Mendelian randomization atlas and genome-wide genetic correlation study

Our research has comprehensively revealed the clear causal relationship between T2DM and specific liver diseases, emphasizing the importance of preventing such diseases in patients with T2DM. These findings not only confirm and expand the existing knowledge framework regarding the relationship between T2DM and liver diseases but also provide new insights for clinical practice and future research directions.

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Publication Details

Journal
European Journal of Gastroenterology & Hepatology
Published
2026-01-28
DOI
https://doi.org/10.1097/meg.0000000000003096
Primary Topic
Genetic Associations and Epidemiology
Type
article
Field-Weighted Citation Impact
0.00
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article

Type 2 diabetes mellitus and liver diseases: a phenome-wide Mendelian randomization atlas and genome-wide genetic correlation study

Huimin Lu, Jin Li, Liyan Xie, Rong Ding et al.
European Journal of Gastroenterology & Hepatology
Genetic Associations and Epidemiology
article

Type 2 diabetes mellitus and liver diseases: a phenome-wide Mendelian randomization atlas and genome-wide genetic correlation study

Huimin Lu, Jin Li, Liyan Xie, Rong Ding, Kaile Guan, Lei Shan, Qi Chen, Yue Zhang, Min Zhou
article en

Abstract

Our research has comprehensively revealed the clear causal relationship between T2DM and specific liver diseases, emphasizing the importance of preventing such diseases in patients with T2DM. These findings not only confirm and expand the existing knowledge framework regarding the relationship between T2DM and liver diseases but also provide new insights for clinical practice and future research directions.

European Journal of Gastroenterology & HepatologyVol. 38(3)
Harbin Medical University (CN), First Affiliated Hospital of Harbin Medical University (CN)
Openalex Percentile: Top 38%
Genetic Associations and Epidemiology
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