Early Use of Fentanyl Increases Risk of Delirium in Patients Transfer to the intensive Care Unit After Cardiac Surgery Immediately: A Target Trial Emulation

The findings of this study, conducted within a TTE framework, indicate that the utilization of fentanyl for pain management during the initial 24 h following cardiac surgery is associated with a higher incidence and earlier onset of postoperative delirium compared to morphine.

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Publication Details

Journal
Journal of Evidence-Based Medicine
Published
2026-02-26
DOI
https://doi.org/10.1111/jebm.70123
Primary Topic
Intensive Care Unit Cognitive Disorders
Type
article
Field-Weighted Citation Impact
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article

Early Use of Fentanyl Increases Risk of Delirium in Patients Transfer to the intensive Care Unit After Cardiac Surgery Immediately: A Target Trial Emulation

Zhongkai Qu, Ningxia He, Liying Huang, Bo Chen et al.
Journal of Evidence-Based Medicine
Intensive Care Unit Cognitive Disorders
article

Early Use of Fentanyl Increases Risk of Delirium in Patients Transfer to the intensive Care Unit After Cardiac Surgery Immediately: A Target Trial Emulation

Zhongkai Qu, Ningxia He, Liying Huang, Bo Chen, Zhigang Wang, Weisheng Chen, Xinya Li, Jun Lyu, Shuna Li, Li Li
article en

Abstract

The findings of this study, conducted within a TTE framework, indicate that the utilization of fentanyl for pain management during the initial 24 h following cardiac surgery is associated with a higher incidence and earlier onset of postoperative delirium compared to morphine.

Journal of Evidence-Based Medicine
Ministry of Education of the People's Republic of China (CN), Jinan University (CN), First Affiliated Hospital of Jinan University (CN)
Good health and well-being
Openalex Percentile: Top 41%
Intensive Care Unit Cognitive Disorders
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