<scp>3D</scp> virtual histology demonstrates tumour connectivity in spread through air spaces ( <scp>STAS</scp> ) of non‐small cell lung cancer
These findings indicate that most STAS types are clusters of cells connected to the main tumour mass. 3D X-ray virtual histological investigation helps to understand the morphological composition and spatial evolution of the tumour, as well as the presence of a tumour larger than that visible in the histological slide. From a radiological and surgical perspective, these findings may influence the assessment of the extent of parenchymal involvement and help guide the surgical approach.
Authors
- Elisa Baratella (ORCID: https://orcid.org/0000-0002-1061-9507)
- Cristina Bottin (ORCID: https://orcid.org/0000-0002-2242-0706)
- Maria Assunta Cova
- F. Martellani
- Stefano Lovadina (ORCID: https://orcid.org/0009-0001-3305-9565)
- Giulia Saccomano (ORCID: https://orcid.org/0000-0003-3078-5008)
- Francesco Brun
Institutions
- University of Trieste (IT)
- Elettra-Sincrotrone Trieste S.C.p.A. (IT)
- Ospedale di Cattinara (IT)
Publication Details
- Journal
- Histopathology
- Published
- 2026-02-26
- DOI
- https://doi.org/10.1111/his.70130
- Primary Topic
- Lung Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00