Association of Cardiovascular‐Kidney‐Syndrome and Brain Macrostructure and Microstructure Injury: A Prospective Cohort Study
Our findings indicate that CKM syndrome severity is associated with abnormalities in brain macrostructure and microstructure. This is evidenced by both progressive white matter microstructural deterioration, which is detectable early, and concomitant, albeit more modest, declines in brain macrostructure. These results underscore the importance of early identification and monitoring of CKM syndrome to help mitigate or delay subsequent decline in brain health.
Authors
- Hao Li (ORCID: https://orcid.org/0000-0001-5463-9529)
- Xing Wang (ORCID: https://orcid.org/0000-0002-8537-7186)
- Xueli Cai
- Yuesong Pan
- Yongjun Wang
- Yilong Wang
- Guanyu Niu
- Yingying Yang
- Jing Jing
- Dandan Liu
Institutions
- Capital Medical University (CN)
- Lishui University (CN)
- Beijing Tian Tan Hospital (CN)
- National Clinical Research Center for Digestive Diseases (CN)
- Lishui Central Hospital (CN)
- Lishui City People's Hospital (CN)
Publication Details
- Journal
- Diabetes Obesity and Metabolism
- Published
- 2026-02-26
- DOI
- https://doi.org/10.1111/dom.70605
- Primary Topic
- Genetic and Kidney Cyst Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00