<scp>KIFC1</scp> is Associated With Sarcomatoid Differentiation, Immune Response, and a Poor Prognosis in Clear Cell Renal Cell Carcinoma

KIFC1 serves as a multifunctional molecule linking epithelial-mesenchymal transition, immune modulation, and treatment resistance. It may be a promising prognostic biomarker and therapeutic target in ccRCC, warranting further functional and clinical investigation.

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Publication Details

Journal
Cancer Medicine
Published
2026-02-26
DOI
https://doi.org/10.1002/cam4.71687
Primary Topic
Renal cell carcinoma treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

KIFC1 is Associated With Sarcomatoid Differentiation, Immune Response, and a Poor Prognosis in Clear Cell Renal Cell Carcinoma

Kenshiro Takemoto, Miki Naito, Hikaru Nakahara, Takao Hinoi et al.
Cancer Medicine
Renal cell carcinoma treatment
article

KIFC1 is Associated With Sarcomatoid Differentiation, Immune Response, and a Poor Prognosis in Clear Cell Renal Cell Carcinoma

Kenshiro Takemoto, Miki Naito, Hikaru Nakahara, Takao Hinoi, Yoshinori Nakano, Keisuke Hieda, Shintaro Akabane, Go Kobayashi, AKIHIRO GORIKI, Nobuyuki Hinata, Hiroyuki Kitano, YOHEI SEKINO, Shunsuke Miyamoto, Keisuke Goto, Kohei Kobatake
article en

Abstract

KIFC1 serves as a multifunctional molecule linking epithelial-mesenchymal transition, immune modulation, and treatment resistance. It may be a promising prognostic biomarker and therapeutic target in ccRCC, warranting further functional and clinical investigation.

Cancer MedicineVol. 15(3)
Hiroshima University (JP), Radiation Effects Research Foundation (JP), Hiroshima University Hospital (JP)
Japan Society for the Promotion of Science
No poverty
Openalex Percentile: Top 40%
Renal cell carcinoma treatment
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