Sodium‐glucose co‐transporter 2 inhibitors and obesity‐associated cancers in people with type 2 diabetes: A real‐world observational study
In this large real-world study of individuals with T2D, initiation of SGLT-2i was not associated with higher or lower rates of OAC compared with DPP-4i. However, initiation of SGLT-2i was associated with a modestly lower rate of the all-cancer outcome, the clinical significance of which remains unclear.
Authors
- Karen E. Brown (ORCID: https://orcid.org/0000-0002-9866-3237)
- Dimitris Papamargaritis (ORCID: https://orcid.org/0000-0001-5044-1515)
- Elina Akalestou (ORCID: https://orcid.org/0000-0001-9316-6680)
- Jonathan Goldney (ORCID: https://orcid.org/0000-0001-8553-8296)
- Testimony Ipaye
- Thomas Yates
- Melanie J Davies
- Kamlesh Khunti
- Francesco Zaccardi
Institutions
- University of Leicester (GB)
- Leicester General Hospital (GB)
- Leicester College (GB)
- University Hospitals of Leicester NHS Trust (GB)
- NIHR Leicester Biomedical Research Centre (GB)
- Imperial College London (GB)
Publication Details
- Journal
- Diabetes Obesity and Metabolism
- Published
- 2026-02-26
- DOI
- https://doi.org/10.1111/dom.70562
- Primary Topic
- Metabolism, Diabetes, and Cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00