Identification of <scp> <i>NTRK3</i> </scp> fusions in plaque‐like <scp>CD34</scp> ‐positive dermal fibroma
NTRK3 gene fusions occur in a subset of plaque-like CD34-positive dermal fibromas, providing additional molecular insight into this rare superficial spindle cell lesion. Together with emerging literature, these findings support a role for recurrent kinase gene rearrangements in a subset of CD34-positive plaque-like superficial spindle cell tumours, while underscoring the continued importance of clinicopathologic correlation in defining this evolving spectrum.
Authors
- Gauri Panse
- Jeffrey M Cloutier
- Iwei Yeh
- Michael Lee
Institutions
- Dartmouth–Hitchcock Medical Center (US)
- University of California, San Francisco (US)
- Yale University (US)
- New York University (US)
Publication Details
- Journal
- Histopathology
- Published
- 2026-02-26
- DOI
- https://doi.org/10.1111/his.70120
- Primary Topic
- Cancer and Skin Lesions
- Type
- article
- Field-Weighted Citation Impact
- 0.00