Malignant Follicular Tumors With Myxoid Mucopolysaccharide‐Like Stroma on Cytology and Histology in a Cat

This case highlights the cytologic and histologic complexity of diagnosing malignant follicular tumors in cats. The presence of abundant myxoid-like mucin-rich stroma may be associated with aggressive biological behavior. Malignant trichoepithelioma should remain a differential diagnosis for basaloid epithelial neoplasms in cats, even in the absence of cytologic evidence of keratinization. This report adds to the limited literature on feline malignant follicular tumors and emphasizes the need for further investigation into their diagnostic criteria and biological behavior.

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Publication Details

Journal
Veterinary Clinical Pathology
Published
2026-02-25
DOI
https://doi.org/10.1111/vcp.70093
Primary Topic
Veterinary Oncology Research
Type
article
Field-Weighted Citation Impact
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article

Malignant Follicular Tumors With Myxoid Mucopolysaccharide‐Like Stroma on Cytology and Histology in a Cat

James Chambers, Shannon L. Donahoe, Reika Ueda, Ester Quilez
Veterinary Clinical Pathology
Veterinary Oncology Research
article

Malignant Follicular Tumors With Myxoid Mucopolysaccharide‐Like Stroma on Cytology and Histology in a Cat

James Chambers, Shannon L. Donahoe, Reika Ueda, Ester Quilez
article en

Abstract

This case highlights the cytologic and histologic complexity of diagnosing malignant follicular tumors in cats. The presence of abundant myxoid-like mucin-rich stroma may be associated with aggressive biological behavior. Malignant trichoepithelioma should remain a differential diagnosis for basaloid epithelial neoplasms in cats, even in the absence of cytologic evidence of keratinization. This report adds to the limited literature on feline malignant follicular tumors and emphasizes the need for further investigation into their diagnostic criteria and biological behavior.

Veterinary Clinical Pathology
The University of Sydney (AU), The University of Tokyo (JP)
Openalex Percentile: Top 40%
Veterinary Oncology Research
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