Impact of <scp>BCG</scp> failure patterns on efficacy of intravesical gemcitabine/docetaxel in high‐risk non‐muscle‐invasive bladder cancer

Gemcitabine/docetaxel demonstrated meaningful activity across all BCG failure types, with late BCG relapsing patients achieving the most favourable outcomes and refractory disease showing the poorest control. These findings underscore the clinical relevance of distinguishing BCG failure subtypes when selecting candidates for post-BCG intravesical gemcitabine/docetaxel and designing future prospective trials.

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Publication Details

Journal
British Journal of Urology
Published
2026-02-25
DOI
https://doi.org/10.1111/bju.70182
Primary Topic
Bladder and Urothelial Cancer Treatments
Type
article
Field-Weighted Citation Impact
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article

Impact of BCG failure patterns on efficacy of intravesical gemcitabine/docetaxel in high‐risk non‐muscle‐invasive bladder cancer

Daniele Dutto, Pietro Scilipoti, R. Pichler, A. Ramos López et al.
British Journal of Urology
Bladder and Urothelial Cancer Treatments
article

Impact of BCG failure patterns on efficacy of intravesical gemcitabine/docetaxel in high‐risk non‐muscle‐invasive bladder cancer

Daniele Dutto, Pietro Scilipoti, R. Pichler, A. Ramos López, Giovanni Tremolada, José Luis Rodríguez Elena, Maurizio Colecchia, Aleksandra Szostek, Valentina Ferrando, Albane MASSIET DU BIEST, José Daniel Subiela, Angelo Occhi, Javier Aranda, Oscar Buisan, Tobias Klatte, A. Aguilera Bazán, Rodolfo Hurle, Shahrokh F Shariat, Mattia Longoni, Roberto Contieri, Olga Katzendorn, Palma Estella Lucena, Marco Moschini, Francesco Soria, Paolo Gontero, Wojciech Krajewski, Ekaterina Laukhtina, David D Andrea, Paolo Zaurito, Benjamin Pradere, Alberto Briganti, Francesco Montorsi, Gautier Marcq, Ana Fernández
article en

Abstract

Gemcitabine/docetaxel demonstrated meaningful activity across all BCG failure types, with late BCG relapsing patients achieving the most favourable outcomes and refractory disease showing the poorest control. These findings underscore the clinical relevance of distinguishing BCG failure subtypes when selecting candidates for post-BCG intravesical gemcitabine/docetaxel and designing future prospective trials.

British Journal of Urology
Université Claude Bernard Lyon 1 (FR), Humanitas University (IT), Innsbruck Medical University (AT), Vita-Salute San Raffaele University (IT), Universidad de Alcalá (ES), Universität Innsbruck (AT), Université Paris Cité (FR), Cornell University (US), Charles University (CZ), Hospital Universitario La Paz (ES), Bellvitge University Hospital (ES), ProMedica Toledo Hospital (US), Centre Hospitalier Universitaire de Lille (FR), Wroclaw Medical University (PL), Comprehensive Cancer Center Vienna (AT), Azienda Ospedaliero Universitaria San Giovanni Battista (IT), Helios Hospital Bad Saarow (DE), Instituto Ramón y Cajal de Investigación Sanitaria (ES), IRCCS Ospedale San Raffaele (IT), Hôpital Bichat-Claude-Bernard (FR), Medizinische Hochschule Brandenburg Theodor Fontane (DE), Hôpital Claude Huriez (FR), Complejo Hospitalario de Cáceres (ES), Karl Landsteiner Society (AT), Hospital Universitario Ramón y Cajal (ES), IRCCS Humanitas Research Hospital (IT), Complejo Hospitalario Universitario de Toledo (ES), Medical University of Vienna (AT), The University of Texas Southwestern Medical Center (US)
No poverty
Openalex Percentile: Top 40%
Bladder and Urothelial Cancer Treatments
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